%0 Journal Article
%T Prophylactic salpingo-oophorectomy & surgical menopause for inherited risks of cancer: the need to identify biomarkers to assess the theoretical risk of premature coronary artery disease
%A Edward OˇŻBrien
%A Nadia Maarouf
%A Vipul Shrivastava
%A Zarah Batulan
%J Archive of "Women's Midlife Health".
%D 2018
%R 10.1186/s40695-018-0037-y
%X Estrogen binding to its receptors activate signaling pathways that promote cell division & proliferation in breast cancer cells (a), and that regulate vasodilation & HSP27 release in the cardiovascular system (b). E2: estrogen, ER: estrogen receptor, Cas9: caspase 9, eNOS: endothelial nitric oxide synthase, HSP27: heat shock protein 27. [34¨C36, 57, 68, 94
%K Atherosclerosis
%K Cardiovascular disease
%K Cardiovascular risk factors
%K Coronary artery disease
%K Estrogen
%K Heat shock protein 27
%K HSP27
%K Inflammatory cytokines
%K Menopause
%K PCSK9
%K Prophylactic salpingo-oophorectomy
%K Retinal vessel analysis
%K Surgical menopause
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297996/