%0 Journal Article
%T GLCCI1 rs37973 is associated with the response of adrenal hormone to inhaled corticosteroids in asthma
%A Chengping Hu
%A Juntao Feng
%A Ling Qin
%A Qiufen Xun
%A Rongli Lu
%A Ruoxi He
%A Xiaozhao Li
%A Xinyue Hu
%J Archive of "The World Allergy Organization Journal".
%D 2019
%R 10.1016/j.waojou.2019.100017
%X Previous studies have demonstrated that glucocorticoid-induced transcript 1 gene (GLCCI1) rs37973 mutant genotype is associated with poor inhaled corticosteroid (ICS) response in asthmatics. As human airway relaxation is regulated by circulation epinephrine, which can be enhanced by corticosteroid. It is unknown whether or not GLCCI1 rs37973 is associated with circulation epinephrine and cortisol concentrations in asthma. The aim of this study is to evaluate these relationships
%K GLCCI1
%K Adrenal hormone
%K Inhaled corticosteroids
%K Asthma
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439416/