%0 Journal Article
%T Collagen Scaffolds in Cartilage Tissue Engineering and Relevant Approaches for Future Development
%A Akon Higuchi
%A Toshiyuki Ikoma
%A Tzu-Cheng Sung
%A Vincent Irawan
%J Archive of "Tissue Engineering and Regenerative Medicine".
%D 2018
%R 10.1007/s13770-018-0135-9
%X Illustration of articular cartilage tissues and concept of cartilage tissue engineering. A Schematic representation of articular cartilage with a lesion in knee. B Articular cartilage consists of multiple zones and is separated with subchondral bone by calcified zones. Some areas are stained with red Safranin O/Fast staining, indicating presence of proteoglycan. Inset shown AC (dotted circle) embedded in cartilage matrix. Scale bar: 20 ¦Ìm. C Flow of cartilage tissue engineering started with biopsy of cartilage tissue and ended with implantation of mature scaffolds into lesions
%K Cartilage tissue engineering
%K Type I collagen
%K Articular chondrocytes
%K Mesenchymal stem cells
%K Hybrid scaffolds
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250655/