%0 Journal Article
%T ¦Â-Cyclodextrin Assisted Liquid¨CLiquid Microextraction Based on Solidification of the Floating Organic Droplets Method for Determination of Neonicotinoid Residues
%J Molecules | An Open Access Journal from MDPI
%D 2019
%R https://doi.org/10.3390/molecules24213954
%X An efficient and environment-friendly microextraction method, namely, ¦Â-cyclodextrin assisted liquid¨Cliquid microextraction, based on solidification of the floating organic droplets method coupled with HPLC is investigated for the sensitive determination of trace neonicotinoid pesticide residues. In this method, ¦Â-cyclodextrin is used as a disperser solvent, while 1-octanol is selected as an extraction solvent. ¦Â-cyclodextrins was found to decrease interfacial tension and increase the contact area between the organic and water phases with the help of centrifugation. A cloudy solution was rapidly formed and then centrifuged to complete phase separation. Various key parameters influencing extraction efficiency were systematically investigated and optimized; they include salt addition, concentration of ¦Â-cyclodextrin, and volume of extraction solvent (1-octanol). Under optimum conditions, good linearity was obtained with coefficient for determination (R 2) greater than 0.99. A low limit of detection, high enrichment factor, and good recovery (83 ¨C 132) were achieved. This proves that the proposed method can be applied to determine trace neonicotinoid pesticide residues in natural surface water samples
%U https://www.mdpi.com/1420-3049/24/21/3954