%0 Journal Article
%T Thermo- and pH-dual responsive polymeric micelles with upper critical solution temperature behavior for photoacoustic imaging-guided synergistic chemo-photothermal therapy against subcutaneous and metastatic breast tumors
%A Chenyang Zhao
%A Huiyan Luo
%A Jie Liu
%A Na Sun
%A Rui Cheng
%A Xian Li
%A Ya Chen
%A Zerong Liu
%A Zhe Yang
%A Zhongmin Tian
%J Theranostics
%D 2018
%I Ivyspring International Publisher
%R 10.7150/thno.26195
%X Chemo-photothermal therapy shows great potential for inhibiting tumor growth. However, achieving maximal chemo-photothermal synergistic efficacy is challenging because of the low efficiency of controllable chemo-drug release in response to external or internal triggers. Thus, a nano-delivery system that could effectively achieve photothermal therapy and dual stimuli-responsive (heat and pH) drug release to inhibit both primary breast tumor growth and metastases is required.
%K upper critical solution temperature (UCST)
%K chemo-photothermal therapy
%K controlled release
%K photoacoustic imaging
%K breast cancer
%U http://www.thno.org/v08p4097.htm