%0 Journal Article
%T Potential Mutations in Uveal Melanoma Identified Using Targeted Next-Generation Sequencing
%A Chuanliang Cui
%A Huan Yu
%A Jiayi Yu
%A Jie Dai
%A Jinyu Yu
%A Jun Guo
%A Junya Yan
%A Longwen Xu
%A Lu Si
%A Lu Yang
%A Meng Ma
%A Tianxiao Xu
%A Ting Yin
%A Xiaowen Wu
%A Xinan Sheng
%A Yan Kong
%A Zhihong Chi
%A Zhiyuan Cheng
%J Journal of Cancer
%D 2019
%I Ivyspring International Publisher
%R 10.7150/jca.26967
%X Background/objective: Uveal melanoma (UM) is the most common intraocular malignancy and has a high tendency to metastasize to the liver. Although primary tumours can be successfully treated, there is currently no effective treatment for metastatic UM. To gain insight into the genetics of UM, we performed the targeted next-generation sequencing (NGS) of UM samples from a non-Caucasian population.
%K uveal melanoma
%K metastasis
%K FOXO1
%K HIF1A.
%U http://www.jcancer.org/v10p0488.htm