%0 Journal Article
%T IgE Sensitization to the Food Allergen Galactose-¦Á-1,3-Galactose is Associated with Coronary Atherosclerosis
%A Alexander J. Schuyler
%A Angela M. Taylor
%A Anh T. Nguyen
%A Coleen A. McNamara
%A Jeffrey M. Wilson
%A Scott P. Commins
%A Thomas A.E. Platts-Mills
%J Journal of Allergy and Clinical Immunology
%D 2018
%R 10.1016/j.jaci.2017.12.467
%X The oligosaccharide galactose-¦Á-1,3-galactose (¦Á-Gal) is the target of IgE in cases
of delayed anaphylaxis to red meat. Sensitization to ¦Á-Gal is more prevalent in the
community than cases of delayed anaphylaxis and is particularly common in the southeastern
United States, a region with high incidence of cardiovascular disease. Additionally,
recent reports have linked mast cells and elevated total IgE with coronary artery
disease. We sought to test the hypothesis that sensitization to ¦Á-Gal represents an
independent risk factor for coronary atherosclerosis.
%U https://www.jacionline.org/article/S0091-6749(17)32367-9/abstract