%0 Journal Article %T HPLC-based activity profiling for pharmacologically and toxicologically relevant natural products ¨C principles and recent examples %A Matthias Hamburger %J Archive of "Pharmaceutical Biology". %D 2019 %R 10.1080/13880209.2019.1606261 %X Context: Discovery of pharmacologically active natural products as starting points for drug development remains important and, for reasons of consumer safety, the identification of toxicologically relevant compounds in herbal drugs %K GABAA receptor %K hERG %K Piper nigrum %K Evodia rutaecarpa %K piperine %K dehydroevodiamine %K hortiamine %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507960/