%0 Journal Article %T Shortened up-dosing with sublingual immunotherapy drops containing tree allergens is well tolerated and elicits dose-dependent clinical effects during the first pollen season %A Katharina Bastl %A Katrin Birkholz %A Kija Shah-Hosseini %A Mark Hess %A Matthias F. Kramer %A Maximilian Bastl %A Nils Y. Breitr¨¹ck %A Petra Zieglmayer %A Ralph M£¿sges %A Silke Allekotte %A Sonja Guethoff %A Uwe Berger %A Van-Anh Dao %J Archive of "The World Allergy Organization Journal". %D 2019 %R 10.1016/j.waojou.2019.100012 %X This study compared a rapid home-based up-dosing schedule for sublingual immunotherapy (SLIT) drops containing tree pollen allergens with two previously established schedules. Furthermore, the clinical effect of the SLIT was investigated with respect to patients¡¯ first pollen season under treatment %K Adherence %K Asthma %K Conjunctivitis %K Immunotherapy %K Pollen allergy %K Pre-seasonal %K Rhinitis %K SLIT %K Sublingual immunotherapy AE %K adverse event %K ARIA %K Allergic Rhinitis and its Impact on Asthma %K IgE %K immunoglobulin E %K N %K number %K PHD %K Patient's Hay Fever Diary %K RCAT %K Rhinitis Control Assessment Test %K SD %K standard deviation %K sIgE %K specific immunoglobulin E %K SLI %K symptom load index %K SLIT %K sublingual immunotherapy %K SmPC %K Summary of Product Characteristics %K TU %K therapeutic units %K V %K visit %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439405/