%0 Journal Article
%T Anti-demineralization effect of desensitizer containing copolymer and sodium fluoride on root dentin ¨C a transverse microradiographic study
%A Haruhiko Hasegawa
%A Hirohisa Arakawa
%A Kazuaki Kawamura
%A Takafumi Nakano
%A Yoshiharu Mukai
%A Yuichi Kunimatsu
%J Biomaterial Investigations in Dentistry
%D 2019
%R https://doi.org/10.1080/23337931.2019.1591967
%X Abstract Objective: To evaluate anti-demineralization effects of dentin desensitizer containing sodium fluoride and methacrylate-co-p-styrene sulfonic acid (MS polymer) on root dentin using transverse microradiography (TMR). Material and methods: Twenty-four dentin specimens were divided into four groups: MSO (no fluoride), MSF (3000£¿ppm F), FJL (9000£¿ppm F), and Control. In MSO and MSF, each desensitizer was rubbed into the dentin surfaces for 10£¿s then left for 20£¿s. In FJL, paste containing 9000£¿ppm F was applied onto the surface for 30£¿s. All specimens, including the Controls, were rinsed with deionized water, dried and an area of their surface exposed to pH 5.0 acidic solution, refreshed every 24£¿h, for 4 days. Sections 300-¦Ìm-thick were assessed by TMR. Mineral profiles and integrated mineral loss (IML) of lesions were analyzed by dedicated software. IML was analyzed with one-way ANOVA and Tukey¡¯s test. Results: MSF and FJL specimens showed high mineral volume % at the surface and in lesions, and significantly lower IML than the other groups (p£¿<£¿.05). Conclusion: Dentin desensitizer containing 3000£¿ppm fluoride and MS polymer has the same anti-demineralization effect as does a fluoride paste containing 9000£¿ppm F
%U https://www.tandfonline.com/doi/full/10.1080/23337931.2019.1591967