%0 Journal Article %T Non %A Sze May Ng %J Clinical Ethics %@ 1758-101X %D 2019 %R 10.1177/1477750919845084 %X The future health of children depends on clinical research which is an important part of medical progress. The principles of the childĄ¯s best interests standards and how it is applied in the context of research are explored. This review will show that there is a need for research involving children but there are gaps in the current legal and ethical framework which are not readily applicable to non-therapeutic research involving children. There are significant challenges in trying to achieve a balance between what is socially good and the obligation to protect children who participate in research %K Ethics %K children %K research %U https://journals.sagepub.com/doi/full/10.1177/1477750919845084