%0 Journal Article %T Evaluating the Effect of a Patient Decision Aid for Atrial Fibrillation Stroke Prevention Therapy %A Alison McClean %A Anita I. Kapanen %A James Hicklin %A Jason G. Andrade %A Jenny MacGillivray %A Larry D. Lynd %A Leanne Kwan %A Nick Bansback %A Peter S. Loewen %A Shahrzad Salmasi %J Annals of Pharmacotherapy %@ 1542-6270 %D 2019 %R 10.1177/1060028019828420 %X Background: Stroke prevention therapy decisions for patients with atrial fibrillation (AF) are complex and require trade-offs, but few validated patient decision aids (PDAs) are available to facilitate shared decision making. Objective: To evaluate the effects of a novel PDA on decision-making parameters for AF patients choosing stroke prevention therapy. Methods: We developed an evidence-based individualized online AF PDA for stroke prevention therapy and evaluated it in a prospective observational pilot study. The primary outcome was decisional conflict. Secondary outcomes were knowledge, usability/acceptability, patient preferences, effects on therapy choices, and participant feedback. Results: 37 participants completed the PDA. The PDA could be completed independently and was well accepted. It significantly decreased the mean decisional conflict score (P < 0.001) and all its subscales and increased participant AF knowledge (P = 0.02). 76% of participants indicated that their individualized therapy attribute ranking was congruent with their values. The PDA-generated best-match therapy was chosen by 70% of participants in decision 1 (no therapy, aspirin, or oral anticoagulant), and 17% for decision 2 (choice of anticoagulant). Among AF patients, 60% chose a different drug than that currently prescribed to them. Conclusion and Relevance: Our PDA was effective for reducing decisional conflict, increasing patient knowledge, eliciting patients¡¯ values, and presenting therapy options that aligned with patients¡¯ values and preferences. Using the PDA revealed that many patients have therapy preferences different from their currently prescribed treatment. The PDA is a practical and potentially valuable tool to facilitate decision making about stroke prevention therapy for AF %K atrial fibrillation %K anticoagulation %K patient decision aid %K shared decision making %K bleeding %K stroke prevention %U https://journals.sagepub.com/doi/full/10.1177/1060028019828420