%0 Journal Article
%T Apathy in Preclinical Alzheimer¡¯s Disease: Psychometric Validation of the Apathy Evaluation Scale
%A Beatrice Lee
%A Carey E. Gleason
%A Cynthia M. Carlsson
%A Emre Umucu
%A Mary Wyman
%A Megan Zuelsdorff
%A Naomi Nystrom
%A Sanjay Asthana
%A Sterling C. Johnson
%A Susan Flowers Benton
%J American Journal of Alzheimer's Disease & Other Dementias£¿
%@ 1938-2731
%D 2019
%R 10.1177/1533317518794020
%X The purpose of the present study was to validate the Apathy Evaluation Scale, self-rated version (AES-S), and assess the severity of apathy in a cognitively healthy middle-aged cohort at risk for Alzheimer¡¯s disease (AD). Three hundred and sixteen middle-aged adults were selected to represent a subset of the Wisconsin Alzheimer¡¯s Disease Research Center Clinical Core: the Investigating Memory in People At-risk, Causes and Treatments cohort. An exploratory factor analysis (EFA) with varimax rotation identified 3 subscales: apathy, disinterest, and social withdrawal factors. Confirmatory factor analysis confirmed the EFA findings. Results indicated acceptable convergent and discriminant validity. The AES-S is a reliable instrument to quantify apathy in cognitively healthy middle-aged individuals at risk for AD. This study demonstrates the AES-S is a psychometrically sound measurement tool for assessing levels of apathy in a cognitively healthy middle-aged cohort at risk for AD
%K apathy
%K Apathy Evaluation Scale
%K Alzheimer¡¯s disease
%K cognitively healthy middle-aged individuals
%K preclinical Alzheimer¡¯s disease
%U https://journals.sagepub.com/doi/full/10.1177/1533317518794020