%0 Journal Article
%T Gas Chromatography每Mass Spectrometry (GC每MS) and Gas Chromatography每Infrared (GC每IR) Analyses of the Chloro
%A Amber Thaxton-Weissenfluh
%A C. Randall Clark
%A Forrest Smith
%A Jack DeRuiter
%A Karim M. Abdel-Hay
%A Tarek S. Belal
%A Younis Abiedalla
%J Applied Spectroscopy
%@ 1943-3530
%D 2019
%R 10.1177/0003702818809998
%X The analytical differentiation of the indole ring regioisomeric chloro-1-n-pentyl-3-(1-naphthoyl)-indoles is described in this report. The regioisomeric chloroindole precursor compounds, N-n-pentyl chloroindole synthetic intermediates, and the target chloro-substituted naphthoylindoles showed the equivalent gas chromatographic elution order based on the position of chlorine substitution on the indole ring. The regioisomeric chloro-1-n-pentyl-3-(1-naphthoyl)-indoles yield electron ionization mass spectra having equivalent major fragments resulting from cleavage of the groups attached to the central indole nucleus. Fragment ions occur at m/z 127 and 155 for the naphthyl and naphthoyl cations common to all indoles having the naphthoyl group substituted at the indole-3 position. Fragments resulting from the loss of the naphthoyl and/or n-pentyl groups from the molecular radical cation yield the cations at m/z 318, 304, 248, and 178. The characteristic (M每17)+ fragment ion at m/z 358 resulting from the loss of OH radical is significant in the mass spectra of all these compounds with 1-naphthoyl groups substituted at the indole-3 position. The vapor phase infrared spectra provide a number of characteristic absorption bands to identify the individual isomers
%K Forensic chemistry
%K designer cannabinoids
%K gas chromatography每infrar汕ed
%K GC每IR
%K gas chromatography每mass spectrometry
%K GC每MS
%K regioisomers
%K indole derivatives
%U https://journals.sagepub.com/doi/full/10.1177/0003702818809998