%0 Journal Article %T Radon Therapy Is Very Promising as a Primary or an Adjuvant Treatment for Different Types of Cancers: 4 Case Reports %A Akihisa Murata %A Hironobu Koga %A Jerry M. Cuttler %A Kenshou Yorozu %A Kiyomi Inoguchi %A Noriko Shimura %A Shuji Kojima %A Takashisa Horii %J Dose %@ 1559-3258 %D 2019 %R 10.1177/1559325819853163 %X We report on the application of radon inhalation therapy to patients with 4 types of cancer: colon, uterine, lung, and liver cell. The radon treatments were given to improve the efficacy of chemotherapy and were potent in all 4 cases. Marker values decreased and disease symptoms were alleviated. We include a lengthy discussion on the mechanism that may be responsible for the observed results. While employing the radon generator to treat the patient with hepatocellular carcinoma, we discovered that a concentration of 6 MBq/m3 was very effective, while 1 MBq/m3 was marginal. This implies different, and rather high, radon concentration thresholds for the treatment of different types of cancer. The evidence from these 4 cases suggests that radon inhalation may be beneficial against various cancer types as an important adjuvant therapy to conventional chemotherapy and for local high-dose radiotherapy, which would address the problem of distant metastasis. A previous case report on 2 patients with advanced breast cancer, who refused chemotherapy or radiotherapy, indicates that radon may be effective as a primary therapy for cancer. Clinical trials should be carried out to determine the best radon concentrations for treatment of other types of cancer, at different stages of progression %K radon therapy %K colon uterine lung liver cancer %K breast cancer %K primary or adjuvant treatment %K optimum radon concentration %K radiation hormesis %U https://journals.sagepub.com/doi/full/10.1177/1559325819853163