%0 Journal Article
%T Electronic Cigarettes: Impact on Lung Function and Fractional Exhaled Nitric Oxide Among Healthy Adults
%A Abdulaziz Sulaiman Almusallam
%A Abdulrahman Muteb Almehaid
%A Fahad Rayan Barayan
%A Inam Zia
%A Muhammad Abdullah Ansary
%A Nawaf Saad Alarifi
%A Sultan Ayoub Meo
%A Thamer Abdulnasir Alsohaibani
%J American Journal of Men's Health
%@ 1557-9891
%D 2019
%R 10.1177/1557988318806073
%X Electronic cigarettes (e-cigarettes) are rapidly becoming an alternative form of nicotine consumption worldwide and a disruptive element in the global health diplomacy. This study aimed to investigate the impact of e-cigarettes on lung function and fractional exhaled nitric oxide (FeNO) among young healthy male adults. Sixty apparently healthy male volunteers were recruited and divided into two groups. Group 1 (e-cigarette-exposed group) consisted of 30 males who were daily e-cigarette users (age 27.07 ¡À 6.00 [mean ¡À SD] years). Group 2 (control group) consisted of 30 males who were not e-cigarette users (age 25.90 ¡À 7.72 [mean ¡À SD] years). Both groups were neither current nor former traditional tobacco users. Age, ethnicity, height, weight, and socioeconomic status were considered using a matched design to investigate the impact of e-cigarette use on lung function and FeNO. The lung function test parameters that were found to be significantly decreased in e-cigarette users compared to their control group were forced expiratory volume in the first second (FEV1), forced expiratory ratio (FEV1/FVC), forced expiratory flow¡ª25% (FEF25%), forced expiratory flow¡ª50% (FEF50%), forced expiratory flow¡ª75% (FEF75%), forced expiratory flow¡ª25%¨C75% (FEF25%¨C75%), and forced expiratory flow¡ª75%¨C85% (FEF75%¨C85%). FeNO was also decreased in e-cigarette users, but it did not reach the level of significance. The use of e-cigarettes significantly impaired various lung function parameters and the pattern of impairment exhibited a peripheral obstructive airway involvement. These findings have a general message for the global health community on the potential harm of e-cigarettes on lung function
%K e-cigarette
%K lung physiology
%K pulmonary function
%K FeNO
%U https://journals.sagepub.com/doi/full/10.1177/1557988318806073