%0 Journal Article %T Feasibility and Impact of a Multicomponent Exercise Intervention in Patients With Alzheimer¡¯s Disease: A Pilot Study %A Arnaldina Sampaio %A Fl¨¢via Borges-Machado %A In¨ºs Marques-Aleixo %A Joana Carvalho %A Joana Meireles %A ¨®scar Ribeiro %J American Journal of Alzheimer's Disease & Other Dementias£¿ %@ 1938-2731 %D 2019 %R 10.1177/1533317518813555 %X This quasi-experimental, nonrandomized study examined the feasibility and impact of a multicomponent (MT) intervention on 7 community-dwelling individuals diagnosed with probable Alzheimer¡¯s disease (AD) at mild to moderate stage. During 6 months, patients with AD and their caregivers were submitted to a biweekly exercise program, including muscle strengthening, aerobics, balance, and postural exercises. The following tests were used: Senior Fitness Test and Incremental Treadmill Test, Disability Assessment for Dementia Scale, Alzheimer Disease Assessment Scale¨CCognitive, and Quality of Life¨CAlzheimer¡¯s. Attendance and retention mean rates were high (86% and 78%, respectively). No adverse events occurred. Results revealed a significant beneficial effect on cardiorespiratory fitness (P = .028), upper (P = .018) and lower (P = .026) body muscle strength, agility (P = .018), and ability to perform daily activities (P = .018). Data suggest that a biweekly MT intervention is feasible to conduct in patients with AD. Findings also suggest a potential positive effect on mitigating cognitive decline and in positively influencing quality of life %K dementia %K physical activity %K quality of life %K functionality %K multimodal intervention %K neurocognitive disorder %U https://journals.sagepub.com/doi/full/10.1177/1533317518813555