%0 Journal Article
%T A Prospective, Controlled, Multicenter Study to Evaluate the Clinical Outcome of Implant Treatment in Women with Osteoporosis/Osteopenia: 5
%A A. K¨¹bler
%A A. Temmerman
%A A. Thor
%A J. Merheb
%A L. Rasmusson
%A M. Quirynen
%J Journal of Dental Research
%@ 1544-0591
%D 2019
%R 10.1177/0022034518798804
%X The impact of osteoporosis on implant treatment is still a matter of debate in the scientific community, as it may possibly lead to higher failure rates. As long-term controlled trials are missing, the aim of this study was to verify the long-term outcome of implants placed in patients with systemic osteoporosis. Postmenopausal women in need of implants underwent bone mineral density measurements in hip and spine, using dual X-ray absorptiometry scans. Based on T-scores, they were divided into 2 groups: group O (osteoporosis group) with a T-score ¡Ü£¿2 or group C (control group) with a T-score of ¡Ý£¿1. Implants were placed in a 2-stage manner and loaded 4 to 8 wk after abutment surgery. Six months after loading and thereafter yearly, clinical and radiographical parameters were assessed. In total, 148 implants were placed in 48 patients (mean age: 67 y [range, 59£¿83]). Sixty-three implants were placed in 20 patients (group O) and 85 implants in 28 patients (group C). After 5 y, 117 implants (38 in group O and 79 in the group C) in 37 patients were assessed. Cumulative survival rate on an implant level was 96.5% (group O: 91.5%; group C: 100.0% [P < 0.05]) and 95.7% (group O: 89.2%; group C: 100.0% [P > 0.05]) on a patient level. The overall marginal bone-level alterations, after 5 y of loading, were £¿0.09 ¡À 0.78 mm (group O: £¿0.15 ¡À 0.50 mm; group C: £¿0.06 ¡À 0.89 mm) on an implant level and £¿0.09 ¡À 0.54 mm (group O: £¿0.18 ¡À 0.43 mm; group C: 0.06 ¡À 0.58 mm) on a patient level (P > 0.05). Oral implant therapy in osteoporotic patients is a reliable treatment option with comparable osseointegration rates, implant survival, and marginal bone-level alterations after 5 y of functional loading (ClinicalTrials.gov NCT00745121)
%K dental implants
%K marginal bone loss
%K postmenopausal
%K long-term outcome
%K survival rates
%K bone mineral density
%U https://journals.sagepub.com/doi/full/10.1177/0022034518798804