%0 Journal Article
%T Optimization of post
%A Hidetake Yabuuchi
%A Masanobu Osame
%A Tsuyoshi Oshita
%J The Neuroradiology Journal
%@ 2385-1996
%D 2019
%R 10.1177/1971400919834693
%X To optimize the post-label delay in single-phase arterial spin labeling (SP-ASL) using multi-phase ASL in 4-dimensional magnetic resonance angiography (4D-MRA). Ten healthy volunteers (six men, four women; age range, 24¨C37 years; mean, 29.1) were enrolled. 4D-MRA and SP-ASL were performed on a 3T magnetic resonance imaging (MRI) scanner. Signal intensities in four cerebral arterial territories (anterior cerebral artery, middle cerebral artery, posterior cerebral artery, and whole area) were measured using both 4D-MRA and SP-ASL, and peak time of maximum intensity through each technique was recorded. Regression analysis was used to determine the correlation between the peak times using 4D-MRA and those using SP-ASL, and the regression function obtained was used to estimate the peak time for SP-ASL (optimum post-label delay) from that obtained for 4D-MRA. The peak time in anterior cerebral artery territory for SP-ASL was expressed as 1.19£¿+£¿0.30£¿¡Á£¿(peak time of 4D-MRA) s, (p£¿=£¿0.017, r2£¿=£¿0.14). The peak time in middle cerebral artery territory for SP-ASL was 0.96£¿+£¿0.58£¿¡Á£¿(peak time of 4D-MRA) s, (p£¿<£¿0.001, r2£¿=£¿0.32). The peak time in posterior cerebral artery territory for SP-ASL was expressed as 0.92£¿+£¿0.58£¿¡Á£¿(peak time of 4D-MRA) s, (p£¿<£¿0.001, r2£¿=£¿0.33). The peak time in whole brain for SP-ASL was expressed as 1.04£¿+£¿0.46£¿¡Á£¿(peak time of 4D-MRA) s, (p£¿<£¿0.001, r2£¿=£¿0.25). The peak time values at 4D-MRA showed potential for use in predicting the optimum post-label delay of SP-ASL
%K Perfusion imaging
%K cerebral perfusion
%K arterial spin labeling
%K post-label delay
%K magnetic resonance imaging
%U https://journals.sagepub.com/doi/full/10.1177/1971400919834693