%0 Journal Article
%T Dilated cardiomyopathy with endocardial fibroelastosis in a juvenile Pallas cat
%A Erwin K. Gudenschwager
%A Jonathan A. Abbott
%A Tanya LeRoith
%J Journal of Veterinary Diagnostic Investigation
%@ 1943-4936
%D 2019
%R 10.1177/1040638719827061
%X Dilated cardiomyopathy (DCM) is a myocardial disease characterized by ventricular chamber dilation associated with systolic myocardial dysfunction in the absence of other cardiac lesions. DCM occasionally develops in conjunction with proliferation of fibroelastic fibers in the endocardium, producing endocardial fibroelastosis (EFE). Although early reports describe EFE as a primary disease, evidence now suggests that EFE may develop as a response to myocardial dysfunction. Echocardiographic evaluation of a 4-wk-old Pallas cat (Otocolobus manul) with respiratory distress revealed enlargement of both atria, enlarged end-systolic left ventricular dimension, and left ventricular dilation. DCM was diagnosed, and the cat was euthanized, given the poor prognosis. Postmortem examination revealed pericardial effusion and biventricular and biatrial enlargement. The interventricular septum and free walls of ventricles were thin. Histologically, the endocardium of the left and right ventricles was diffusely thickened; Verhoeff¨CVan Gieson staining of the left ventricular endocardium revealed a moderate amount of endocardial accumulation of elastin and collagen. These fibers were more prominent in papillary muscles and around coronary blood vessels. Based on these findings, we diagnosed DCM with EFE. Cardiac diseases are rarely diagnosed in wild felids
%K Dilated cardiomyopathy
%K endocardial fibroelastosis
%K Felis
%K Pallas cats
%K zoo
%U https://journals.sagepub.com/doi/full/10.1177/1040638719827061