%0 Journal Article
%T Short
%A A Hope Jahren
%A Brenda M Davy
%A Elaina L Marinik
%A Jyoti Savla
%A Lori B Moore
%A Sarah V Liu
%A Tanya M Halliday
%A Valisa E Hedrick
%J Nutrition and Health
%@ 2047-945X
%D 2018
%R 10.1177/0260106018799522
%X Consumption of added sugars (AS) and sugar-sweetened beverages (SSB) may adversely affect adolescents¡¯ weight and cardiovascular disease risk. Reliance on self-reported dietary assessment methods is a common research limitation, which could be overcome by dietary intake biomarkers. The investigation was a proof-of-concept study to evaluate the proposed carbon isotope ratio (¦Ä13C) biomarker of AS intake in adolescents, using a controlled feeding design. Participants (n = 33, age 15.3 years, 53% female) underwent two seven-day controlled feeding periods in a randomly assigned order. Diets were matched in composition except for AS content (5% or 25% of total energy). Fasting fingerstick blood samples were collected daily during each diet period. Fingerstick ¦Ä13C values changed from day 1 to 8 by ¨C0.05 ¡À 0.071¡ë on 5% AS, and +0.03 ¡À 0.083¡ë on 25% AS (p ¡Ü 0.001). Reliability was demonstrated between day 7 and 8 ¦Ä13C values on the 5% (ICC = 0.996, p ¡Ü 0.001) and 25% (ICC = 0.997, p ¡Ü 0.001) AS diets. Larger scale investigations are warranted to determine if this technique could be applied to population-level research in order to help assess the effectiveness of interventions aimed at reducing the consumption of AS or SSB intake
%K Added sugar
%K adolescents
%K biomarker dietary assessment
%K validation
%U https://journals.sagepub.com/doi/full/10.1177/0260106018799522