%0 Journal Article
%T Optical coherence tomography angiography in myopic choroidal neovascularization after intravitreal ranibizumab
%A Francesca Amoroso
%A Gilda Cennamo
%A Giuseppe de Crecchio
%A Mariacristina Alfieri
%A Nunzio Velotti
%A Stefano Schiemer
%J European Journal of Ophthalmology
%@ 1724-6016
%D 2019
%R 10.1177/1120672118785495
%X To describe the optical coherence tomography angiography characteristics of myopic patients with choroidal neovascularization secondary to pathologic myopia during ranibizumab therapy. Nineteen patients were enrolled in this prospective study (13 females, 6 males, mean age 55.25£¿¡À£¿9.63£¿years) for a total of 20 eyes examined (14 right eyes, 6 left eyes). Images were analyzed independently by two examiners. Mean follow-up was 5.75£¿¡À£¿1.88£¿months, with a mean intravitreal injections of 1.90£¿¡À£¿0.44. Mean best-corrected visual acuity at baseline was 0.39£¿¡À£¿0.18 logMAR versus 0.26£¿¡À£¿0.16 logMAR 6£¿months after treatment. The neovascular area (Z£¿=£¿¨C2.091, p£¿=£¿0.037) was significantly reduced after treatment, whereas vessel density was not (Z£¿=£¿¨C1.848, p£¿=£¿0.065). Moreover, the best-corrected visual acuity was increased (Z£¿=£¿¨C3.055, p£¿=£¿0.002). Neovascular area was significantly correlated with best-corrected visual acuity, at both baseline and follow-up (p£¿<£¿0.05). Our data suggest that optical coherence tomography angiography is a reproducible non-invasive examination with which to monitor changes in the neovascular area in patients with pathologic myopia treated with ranibizumab
%K Optical coherence tomography angiography
%K ranibizumab
%K choroidal neovascularization
%K myopia
%K vessel density
%U https://journals.sagepub.com/doi/full/10.1177/1120672118785495