%0 Journal Article
%T Relapsed/refractory thrombotic thrombocytopenic purpura treated with N
%A Ali Do£żan
%A Cengiz Demir
%A Sinan Demircio£żlu
%A £żmer Ekinci
%J Scottish Medical Journal
%@ 2045-6441
%D 2018
%R 10.1177/0036933018775240
%X Thrombotic thrombocytopenic purpura is a rare condition that presents with microangiopathic haemolytic anaemia, thrombocytopaenia, fever, renal impairment and neurological symptoms. Plasma exchange is a lifesaving treatment for this condition. However, some cases may be non-responsive to plasma exchange, or loss of response may occur. Treatment options for refractory cases include high-dose corticosteroids, rituximab, vincristine, cyclophosphamide, splenectomy, bortezomib and N-acetylcysteine. We present a refractory case of thrombotic thrombocytopenic purpura responding to the last of these therapies
%K Thrombotic thrombocytopenic purpura
%K relapsed
%K refractory
%K N-acetylcysteine
%U https://journals.sagepub.com/doi/full/10.1177/0036933018775240