%0 Journal Article %T Cardiac arrest as an age %A Alexander Niessner %A Alexander Simon %A David-Jonas Rothgerber %A Feras El-Hamid %A Georg Goliasch %A Jan Niederd£¿ckl %A Johann Wojta %A Lorenz Koller %A Patrick Sulzgruber %A Sebastian Schnaubelt %J European Heart Journal: Acute Cardiovascular Care %@ 2048-8734 %D 2019 %R 10.1177/2048872618781370 %X The development of cardiac arrhythmias resulting in cardiac arrest represents a severe complication in patients with acute myocardial infarction. While the worsening of the prognosis in this vulnerable patient collective is well known, less attention has been paid to its age-specific relevance from a long-term perspective. Based on a clinical acute myocardial infarction registry we analysed 832 patients with acute myocardial infarction within the current analysis. Patients were stratified into equal groups (n=208 per group) according to age in less than 45 years, 45¨C64 years, 65¨C84 years and 85 years and older via propensity score matching. Multivariate Cox regression analysis was used to assess the age-dependent influence of cardiac arrest on mortality. The total number of cardiac arrests differed significantly between age groups, demonstrating the highest incidence in the youngest population with 18.8% (n=39), and a significantly lower incidence by increasing age (£¿11.6%; P=0.01). After a mean follow-up time of 8 years, a total of 264 patients (31.7%) died due to cardiovascular causes. While cardiac arrest was a strong and independent predictor for mortality within the total study population with an adjusted hazard ratio of 3.21 (95% confidence interval 2.23¨C4.61; P<0.001), there was no significant association with mortality independently in very young patients (<45 years; adjusted hazard ratio of 1.73, 95% confidence interval 0.55¨C5.53; P=0.35). We found that arrhythmias resulting in cardiac arrest are more common in very young acute myocardial infarction patients (<45 years) compared to their older counterparts, and were able to demonstrate that the prognostic value of cardiac arrest on long-term mortality in patients with acute myocardial infarction is clearly age dependent %K Cardiac arrest %K prognosis %K premature acute myocardial infarction %K outcome %U https://journals.sagepub.com/doi/full/10.1177/2048872618781370