%0 Journal Article
%T Pure delta
%A Erich Seifritz
%A Eva-Maria Pichler
%A Patrik Roser
%A Wolfram Kawohl
%J The International Journal of Psychiatry in Medicine
%@ 1541-3527
%D 2019
%R 10.1177/0091217418791455
%X Anecdotal reports and preliminary studies suggest a therapeutic potential of cannabis in Tourette syndrome. We report the case of a female patient suffering from treatment-resistant Tourette syndrome. Guideline-directed antipsychotic treatment with risperidone and aripiprazole as well as pure delta-9-tetrahydrocannabinol had no significant effect on Tourette syndrome symptomatology. Following administration of a daily dosage of 10 mg delta-9-tetrahydrocannabinol combined with 20 mg cannabidiol (CBD), the patient showed a rapid and highly significant improvement in the Yale Global Tic Severity Scale. It can be speculated whether the beneficial effects may rely on the pharmacological properties of cannabidiol
%K Tourette syndrome
%K tic disorders
%K cannabis
%K delta-9-tetrahydrocannabinol
%K cannabidiol
%U https://journals.sagepub.com/doi/full/10.1177/0091217418791455