%0 Journal Article
%T Study on Molecular Mechanism of Yiqing Capsule in Treating Upper Respiratory Tract Infection Based on Network Pharmacology
%A Yanwu Zhao
%A Junhui Hu
%J Chinese Medicine
%P 1-8
%@ 2151-1926
%D 2020
%I Scientific Research Publishing
%R 10.4236/cm.2020.111001
%X <div style=\"text-align:justify;\">
	<b><span style=\"font-family:Verdana;\">Objective: </span></b><span \"=\"\"><span style=\"font-family:Verdana;\">To investigate the possible mechanism of Yiqing
Capsules in the treatment of upper respiratory tract infection based on network
pharmacology. </span><b><span style=\"font-family:Verdana;\">Methods: </span></b><span style=\"font-family:Verdana;\">The main active components of Yiqing Capsules were
selected on TCMSP database; the targets of upper respiratory tract infection were
selected on GeneCards database. The drug-compound-target network and PPi network
were constructed through STRING database and soft Cytoscape 3.7.2. Soft R was used
to perform GO enrichment analysis and KEGG pathway enrichment analysis of main targets. </span><b><span style=\"font-family:Verdana;\">Results</span></b><span style=\"font-family:Verdana;\">: According to the screening conditions, 48 active compounds and
171 related targets were obtained. GO enrichment analysis obtained 2333 items,
KEGG pathway enrichment analy</span><span style=\"font-family:Verdana;\">sis obtained 2248
items, including Kaposi sarcoma-associated herpesvirus infection, Human cytomegalovirus
infection, Epstein-Barr virus infection, PI3K-Akt signaling pathway, etc. </span><b><span style=\"font-family:Verdana;\">Conclusion</span></b><span style=\"font-family:Verdana;\">:
Yiqing capsules play a therapeutic role in upper respiratory tract infection
through multi-target and multi-pathway.</span></span>
</div>
%K Yiqing Capsule
%K Upper Respiratory Tract Infection
%K Network Pharmacology
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=100705