%0 Journal Article
%T Reproductive Hormone Profiles and Their Relationships with Sexual Function in Patients with Prostate Cancer after Rapid Prostatectomy in Benin City
%A Babatunde Ishola Gabriel Adejumo
%A Omolei Lilian Williams
%A Efosa Bolaji Odigie
%A Ifeoma Gloria Unachukwu
%A Oladimeji Nasiru Abdulrahman
%A Uchechukwu Dimkpa
%A Simon Uzor
%A Oyarazi Margaret Adebowale
%A Ojo Moses Oke
%J Advances in Sexual Medicine
%P 119-130
%@ 2164-5205
%D 2020
%I Scientific Research Publishing
%R 10.4236/asm.2020.104008
%X There
are limited studies examining the relationship between serum reproductive
hormone levels and sexual functions among prostate cancer (PCa) patients after
rapid prostatectomy (RP). Aim: The present study aimed at evaluating the
correlation between post-operative serum levels of some male reproductive
hormones of PCa patients and their sexual functions in the months following RP.<span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">A total
of 20 male patients with clinically localized PCa who had undergone RP within
the last 12 months prior to commencement of the study, were invited to
participate.</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">The</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">postoperative serum levels of their luteinizing hormone (LH), follicle
stimulating hormone (FSH) and total testosterone (Te) were measured. They also
completed a structured health and lifestyle questionnaire to obtain information
on their demographic characteristics and detailed medical history.</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">Our
data indicated normal mean levels of post-operative Te (4.34 ¡À 4.38 ng/ml) in
the patients following RP, while the mean levels of FSH (39.24 ¡À 34.12 miu/ml)
and LH (21.67 ¡À 25.73 miu/ml) were on the increase and far above normal ranges
for healthy men. Data indicated a significant positive correlation between Te
and frequency of sexual intercourse (r = 508; p &lt; 0.05), libido (r = 0.429;
p &lt; 0.05) and penile erection (r = 0.494; p &lt; 0.05). However, no
significant correlations were found between FSH or LH and any of the sexual
function parameters.</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">The present study indicated that radical prostatectomy affected
reproductive hormones by increasing LH and FSH concentrations above normal
ranges for healthy men, while Te
%K Reproductive Hormone
%K Sexual Function
%K Prostate Cancer
%K Rapid Prostatectomy
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=103903