%0 Journal Article
%T A Perspective on Microneedle-Based Drug Delivery and Diagnostics in Paediatrics
%J Journal of Personalized Medicine | An Open Access Journal from MDPI
%D 2019
%R https://doi.org/10.3390/jpm9040049
%X Microneedles (MNs) have been extensively explored in the literature as a means to deliver drugs in the skin, surpassing the stratum corneum permeability barrier. MNs are potentially easy to produce and may allow the self-administration of drugs without causing pain or bleeding. More recently, MNs have been investigated to collect/assess the interstitial fluid in order to monitor or detect specific biomarkers. The integration of these two concepts in closed-loop devices holds the promise of automated and minimally invasive disease detection/monitoring and therapy. These assure low invasiveness and, importantly, open a window of opportunity for the application of population-specific and personalised therapies. View Full-Tex
%U https://www.mdpi.com/2075-4426/9/4/49