%0 Journal Article
%T A BRAF V600E Mutation in RET-Negative Medullary Thyroid Cancer
%A Osuna
%A Patricia Mejia
%A Robbins
%A Richard J.
%A Shakil
%A Jawairia
%A Thomas
%A Jessica S.
%J -
%D 2020
%R https://doi.org/10.1155/2020/7641940
%X We report the case of a woman with a sporadic medullary thyroid carcinoma. Genomic analysis found that her tumor did not contain any common RET mutations but did harbor a BRAF V600E mutation. Only one other well-confirmed example of the BRAF V600E mutation has been reported in an MTC patient. We conclude that this common BRAF mutation may independently drive neoplastic transformation of human parafollicular C cells
%U https://www.hindawi.com/journals/crie/2020/7641940/