%0 Journal Article
%T Lessons Learned from Three Different Acellular Dermal Matrices in Direct-to-Implant Breast Reconstruction
%A Claas Spengler
%A Roland Mett
%A Frank Masberg
%A Peter M. Vogt
%A Tobias R. Mett
%J Modern Plastic Surgery
%P 22-35
%@ 2164-5280
%D 2021
%I Scientific Research Publishing
%R 10.4236/mps.2021.111004
%X The aim of the study was to show significant differences regarding postoperative complications and outcomes using three different Acellular Dermal Matrices (ADM), namely Epiflex®, Strattice® and Braxon®, in immediate implant-based subpectoral breast reconstruction cases. Background: The use of Acellular Dermal Matrices for implant-based breast reconstruction cases continues to evolve. There is a wide variety of products which differ significantly in their biological features. It remains unclear if and how these differences manifest in clinical practice. Methods: 82 cases of primary breast reconstruction in the Department of Plastic and Aesthetic Surgery of HELIOS Clinics Schwerin, Germany between 2010 and 2018 were analyzed. 25 patients received Strattice® acellular dermal matrix (SADM), 22 cases Epiflex® acellular dermal matrix (EADM) and the remaining 35 cases Braxon® acellular dermal matrix (BADM). The mean follow-up was 1.8 years. Cases were analyzed regarding minor or major complications and rate of capsular contracture grade III or IV (Baker Classification). Results: The overall complication rate was 34.1% for all groups (SADM = 40%, EADM = 50%, BADM = 20%, p-value = 0.051). Of all cases, 6 patients underwent implant exchange or secondary autologous reconstruction due to capsular contracture (7.3%). The mean time between revision due to capsular contracture and reconstruction was 35.8 ¡À 14.4 months. 50% of patients, who developed capsular contracture, received postoperative radiation. Mean hospitalization time was 8.2 ¡À 3 days (SADM = 8 ¡À 3.2 days, EADM = 10 ¡À 2.8 days, BADM = 6 ¡À 1.3 days). There were no significant differences between all three groups for demographics, overall complication rate or capsular contracture. However, patients receiving Braxon® matrix showed
%K Breast Reconstruction
%K Acellular Dermal Matrix
%K ADM
%K Direct-to-Implant
%K DTI
%K Immediate Breast Reconstruction
%K IBR
%K Breast Cancer
%K Skin Sparing Mastectomy
%K EPIFLEX
%K Strattice
%K BRAXON
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=106470