%0 Journal Article %T Mathematical modelling of fluid flow and solute transport to define operating parameters for in vitro perfusion cell culture systems %A Bhumika Singh %A Lauren Hyndman %A Nigel J. Mottram %A Sean McGinty %A Sean McKee %A Steven D. Webb %J - %D 2020 %R 10.1098/rsfs.2019.0045 %X In recent years, there has been a move away from the use of static in vitro two-dimensional cell culture models for testing the chemical safety and efficacy of drugs. Such models are increasingly b.. %U https://royalsocietypublishing.org/doi/10.1098/rsfs.2019.0045