%0 Journal Article %T Multiscale modelling of drug transport and metabolism in liver spheroids %A Amy L. Harding %A Craig Murdoch %A Dominic P. Williams %A Helen E. Colley %A Jonathan A. Kyffin %A Joseph A. Leedale %A Parveen Sharma %A Rachel N. Bearon %A Steven D. Webb %J - %D 2020 %R 10.1098/rsfs.2019.0041 %X In early preclinical drug development, potential candidates are tested in the laboratory using isolated cells. These in vitro experiments traditionally involve cells cultured in a two-dimensional m.. %U https://royalsocietypublishing.org/doi/10.1098/rsfs.2019.0041