%0 Journal Article
%T Prognostic Value of Vitamin D Status in Pediatric Patients with Acute Kidney Injury in Tanta University Emergency Hospital, Egypt
%A Mohamed A El-Gamasy
%A Mohmed M. Abdelmageed
%A Mohsen M Eldeeb
%J -
%D 2017
%X Background: AKI is an independent predictor of morbidity and mortality for   critically ill children at Pediatric Emergency Departement (PED) which are liable   for vitamin D deficiency. It is proposed that vitamin D concentration may be either   a biomarker or a co-factor of survival in PED. The aim of this work is to assess   serum 25-(OH)D level in critically ill pediatric patients with AKI at PED within the   1st 24 hours of admission and evaluate its correlation with duration of hospital stay   and mortality outcome.
Subjects and methods: This study was conducted upon 80 critically ill pediatric   patients with AKI during the first 24 hours after hospital admission. AKI was   diagnosed according to the Acute Kidney Injury Network (AKIN) criteria for serum   creatinine. We analyzed the demographic data, PRISM III for severity of illness,   CBC, CRP, serum Ca, serum Phosphorus, serum 25(OH)D and its correlations with   studied variables. We compared between vitamin D severely deficient, insufficient   and sufficient subgroup of patients.
Results: Vitamin D deficiency occurs in two third of studied patients versus one   third of studied controls. There is a significant negative correlation between vitamin   D level and age of patients, sepsis, death probability and serum phosphorus level,   but there is a significant positive correlation between vitamin D level and serum   calcium levels. There was statistically significant increase in death outcome with   increased number of system failure, PRISM III score, decreased weight, height   percentiles and sepsis, so they can be considered as predictors of mortality. ROC   curves denote that 25 (OH) D levels are more valid than CRP in prediction of   mortality.
Conclusion: Vitamin D deficiency was associated with higher incidence of sepsis   and mortality.
%K AKI (Acute Kidney Injury)
%K 25(OH)D
%K PRISM III score
%K Mortality
%K Emergency
%K list of open access journals
%K open access
%K open access journals
%K open access publication
%K open access publisher
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%K open access journal articles
%K imedpub
%K imedpub publishing
%K insight medical publishing
%K imedpub online
%U https://www.imedpub.com/articles/prognostic-value-of-vitamin-d-status-in-pediatric-patients-with-acute-kidney-injury-in-tanta-university-emergency-hospital-egypt.php?aid=20319