%0 Journal Article %T A systematic review and meta-analysis of clinical and functional outcomes of artificial urinary sphincter implantation in women with stress urinary incontinence %A Bara Barakat %A Knut Franke %A Sameh Hijazi %A Samer Schakaki %A Thomas-Alex %A Ulrich Gauger %A Viktoria Hasselhof %A er Vˋgeli %J Arab Journal of Urology %D 2020 %R https://doi.org/10.1080/2090598X.2020.1716293 %X ABSTRACT Objective To evaluate the complications and results of artificial urinary sphincter (AUS) implantation in women with stress urinary incontinence (SUI). Methods A selective database search using keywords (1990每2019) was conducted to validate the effectiveness of the AUS in women. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were utilised. The meta-analysis included 964 women (15 studies) with persistent SUI. The Newcastle-Ottawa score was used to determine the quality of the evidence in each study. The success rate and complications associated with the AUS were analysed. Results Meta-analysis of the published studies showed that complete continence was achieved at a mean rate of 79.6% (95% confidence interval [CI] 72.2每86.6%) and a significant improvement was achieved in 15% (95% CI 10每25%). The mean (range) follow-up was 22 (6每204) months. The mean number of patients per study was 68. The mean (range) explantation rate was 13 (0每44)%. Vaginal erosion occurred in a mean (range) of 9 (0每27)% and mechanical complications in 13 (0每47)%. Infections accounted for 7% of the complications. The total mean (range) revision rate of the implanted AUS was 15.42 (0每44)%. The mean (range) size of the cuff used was 6.7 (5每10) cm. Conclusion Our present analysis showed that implantation of an AUS in women with severe UI is an effective treatment option after failure of first-line therapy. However, the currently available study population is too small to draw firm conclusions. Abbreviations AMS: American Medical Systems; AUS: artificial urinary sphincter; EAU: European Association of Urology; LE: Level of Evidence; PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses; QoL: quality of life; SHELTER: Services and Health for Elderly in Long TERm care (study); SUI: (stress) urinary incontinenc %U https://www.tandfonline.com/doi/full/10.1080/2090598X.2020.1716293