%0 Journal Article
%T Synthesis and Microbial Activity of Manganese (II) and Cobalt (III) Complexes of 3-Methoxy-4-Hydroxyphenylmethyelene (2- Hydroxyphenyl) Amine
%J American Journal of Applied Chemistry
%@ 2330-8745
%D 2019
%X Transition metal complexes of Mnanganese (II) and Cobalt (III) were synthesized from the Schiff¡¯s base ligand, 3-methoxy-4-hydroxyphenylmethyelene (2-hydroxyphenyl) amine which is derived from vanillin and 2-aminohpenol by the reaction of the metal ions. The Structural features of these complexes were obtained from their elemental analyses, magnetic susceptibility, molar conductance, FT-IR, electronic spectra, and Atomic Absorption Spectroscopic studies. In order to study the binding modes of the ligand (Schiff¡¯s base) with metal ions in the complexes, the FT- IR spectrum of the free ligand was compared with the spectra of its complexes. The spectral data suggest the involvement of phenolic oxygen and azomethane nitrogen in coordination to the central metal ions. On the basis of spectral studies and magnetic susceptibility measurements, an octahedral geometry has been assigned for both complexes. The free ligand and its metal complexes were tested in vitro against bacteria (Escherichia coli, Staphylococcus aureus) and fungi (Aspergillus Niger, Colletotricum) in order to assess their antimicrobial activities. And the results indicated that all compounds are effective against both tested bacteria and fungi though their effects are dose dependent. The free ligand showed higher activities than its complexes in both bacteria and fungi case, which suggests the promising potential of the ligand for both bacterial and fungi test
%K Antimicrobial Activities
%K Schiff¡¯s Base Ligand
%K Spectral Studies
%K Transition Metal Complexes
%U http://www.sciencepublishinggroup.com/journal/paperinfo?journalid=227&doi=10.11648/j.ajac.20190703.13