%0 Journal Article
%T Berberine Chloride and Hyperthermia Promote Osterix Expression and Suppress Cell Cycle Genes in Osteosarcoma Cells
%A Alyaa R Rajih AL-Khateeb
%A Dr
%A Gabriele Froemming
%A Mohammed Ali Nashiry
%J -
%D 2018
%X Objectives: The aim of the current study was to investigate the effects of berberine chloride and various heat conditions on the gene expression of Osterix, RUNX-2, RANKL, CDK2, CDK4, IL-6 and IL-11.
%K Six groups of cells were treated with hyperthermia for 1 h: Two groups at mild
%K two at moderate and two at severe hyperthermia (39
%K 43 and 45¡ãC respectively). Berberine chloride (80 ¦Ìg/mL) was selected for treating one group of mild
%K moderate and severe hyperthermia (combination). All treated groups were recovered at 37¡ãC for 24 h. Another exposure for hyperthermia (1 h) and recovery for 3 h at 37¡ãC were applied.
%U http://ust.edu/ojs/index.php/yjmp/article/view/1403