%0 Journal Article
%T Evaluation of Hypoglycemic Activity of Boswellia carterii and Cissus rotundifolia in Streptozotocin/Nicotinamide-Induced Diabetic Rats
%A Adel M. Al-Battah
%A Ali A. Al-Mehdar
%J -
%D 2016
%X Objective: To evaluate the hypoglycemic activity of Boswellia carterii and Cissus rotundifolia in rats compared to that of glibenclamide and metformin as common oral hypoglycemic drugs.
%K Thirty-six male Wistar rats
%K divided into six groups of six rats each
%K were assigned into diabetic and non-diabetic groups. Diabetes was induced in rats by single intraperitoneal administration of streptozotocin (65 mg/kg b.w.) and nicotinamide (110 mg/kg b.w.). The first two groups were normal and diabetic controls
%K whereas the other four diabetic groups were treated with water extracts of the medicinal plants
%K B. carterii (100 mg/kg b.w.) and C. rotundifolia (100 mg/kg b.w.)
%K glibenclamide (5 mg/kg b.w.) and metformin (150 mg/kg b.w.). Body weight and serum glucose were measured on days 1
%K 7
%K 14
%K 21 and 28. Serum cholesterol and triglyceride levels were also measured.
%U http://ust.edu/ojs/index.php/yjmp/article/view/959