%0 Journal Article
%T Correlation between sleep duration and hypertension: a dose-response meta-analysis
%J -
%D 2018
%R https://doi.org/10.1038/s41371-018-0135-1
%X To deeply investigate the correlation between sleep duration and hypertension. The electronic databases Cochrane Library, Pubmed and Embase updated to December 2017 were retrieved, and manual searching for paper-based documents was also performed. After studies were selected according to the predefined screening criteria, their qualities were assessed using Newcastle-Ottawa Scale. Based on R 3.43 software, the association between sleep duration and hypertension was analyzed by dose-response meta-analysis, using relative risk (RR) and 95% confidence interval (95% CI) as effect indexes. Furthermore, publication bias of the eligible studies was evaluated using Egger¡¯s test. In addition, sensitivity analysis was conducted through ignoring one study per time and then observing its influences on the pooled results. A total of 9 studies (involving 48525 objects) were included in this dose-response meta-analysis, which had high qualities. The differences in£¿¡Ü5£¿h vs. 7£¿h, 6£¿h vs. 7£¿h, and 9£¿h vs. 7£¿h groups had statistical significances, suggesting that hypertension risk was higher for shorter sleep duration (P£¿<£¿0.05). There was no significant difference in >9£¿h vs. 7£¿h group. No publication bias was found for the eligible studies, indicating that our results were highly credible (t£¿=£¿0.030, P£¿=£¿0.9766). However, the pooled results were reversed after ignoring each included study per time. Dose-response meta-analysis showed that the hypertension risk reduced for 0.3207% when the sleep duration increased by 1£¿h. Shorter sleep duration contributes to the increase of hypertension risk
%U https://www.nature.com/articles/s41371-018-0135-1