%0 Journal Article
%T Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
%J -
%D 2019
%R https://doi.org/10.1016/j.ccell.2019.01.020
%X £¿ Phosphorylation of PTEN at tyrosine 240 (pY240) by FGFR2 mediates IR resistance £¿ pY240-PTEN plays a critical role in DNA damage repair £¿ pY240-PTEN associates with chromatin DNA through interaction with Ki-67 £¿ Blocking pY240-PTEN using FGFR inhibitors sensitizes tumors to ionizing radiatio
%U https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30054-6