%0 Journal Article
%T The Direct Molecular Target for Imipridone ONC201 Is Finally Established
%J -
%D 2019
%R https://doi.org/10.1016/j.ccell.2019.04.010
%X In this issue of Cancer Cell, Ishizawa et al. describe the hyperactivation of ClpP as a strategy in cancer therapy. They discovered ONC201, a clinical-stage compound, as a potent activator of ClpP and established that ClpP activation is responsible for the antitumor activity of imipridone ONC201
%U https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30205-3