%0 Journal Article
%T Vitamin K2-Dependent GGCX and MGP Are Required for Homeostatic Calcium Regulation of Sperm Maturation
%J -
%D 2019
%R https://doi.org/10.1016/j.isci.2019.03.030
%X £¿ Epididymal sperm maturation requires VK2-dependent GGCX-mediated MGP carboxylation £¿ A GGCX SNP mutation is found in infertile men suffering from asthenozoospermia £¿ Carboxylated-MGP regulates intercellular calcium signaling in the epididymal lumen £¿ Calcium-regulated MGP binds to proteins in a biphasic-manner and favors low level
%U https://www.cell.com/iscience/fulltext/S2589-0042(19)30096-3