%0 Journal Article
%T A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK
%J -
%D 2019
%R https://doi.org/10.1016/j.ccell.2019.01.009
%X £¿ Innovative bioinformatics pipeline reveals FAK as candidate synthetic lethal with G¦Áq £¿ FAK is a central mediator of the GNAQ-driven oncogenic signaling circuitry £¿ FAK activates YAP by MOB1 phosphorylation resulting in Hippo pathway inhibition £¿ FAK represents a potential precision therapeutic target for uveal melanoma treatmen
%U https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30043-1