%0 Journal Article
%T Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality
%J -
%D 2019
%R https://doi.org/10.1016/j.ccell.2019.03.014
%X £¿ Activation of the mitochondrial ClpP induces p53-independent cancer cell lethality £¿ Imipridones are allosteric agonists of ClpP, being tested in human clinical trials £¿ ClpP activation increases proteolysis of mitochondrial proteins £¿ ClpP-mediated mitochondrial proteolysis impairs mitochondrial respiratory functio
%U https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30160-6