%0 Journal Article
%T Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas
%J -
%D 2019
%R https://doi.org/10.1016/j.ccell.2019.04.004
%X £¿ H3K27M mutant gliomas exhibit an enhancer landscape reflecting lineage of origin £¿ Elevated H3K27 acetylation is pervasively distributed across the epigenome £¿ Repeat element expression is de-repressed by H3K27M mutation £¿ H3K27M cells are more vulnerable to DNA demethylation triggering viral mimicr
%U https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30199-0