%0 Journal Article %T Evolution of Relapse-Proficient Subclones Constrained by Collateral Sensitivity to Oncogene Overdose in Wnt-Driven Mammary Cancer %J - %D 2019 %R https://doi.org/10.1016/j.celrep.2018.12.096 %X £¿ Wnt-driven mammary cancers maintain dependence on sub-maximal Wnt signaling £¿ Rescue mutations destined to subvert targeted therapy carry a fitness cost £¿ Oncogene overdose imposes negative selection, leading to turnover of rescue subclone %U https://www.cell.com/cell-reports/fulltext/S2211-1247(18)32056-4