%0 Journal Article
%T The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair
%J -
%D 2019
%R https://doi.org/10.1016/j.cell.2018.10.053
%X £¿ Replicative helicase CMG bypasses DNA-protein crosslinks on its translocation strand £¿ RTEL1, an accessory helicase, facilitates bypass by unwinding DNA beyond the DPC £¿ CMG slows after bypass, likely due to uncoupling from DNA synthesis £¿ Bypass triggers DPC proteolysis and prevents accidental degradation of CM
%U https://www.cell.com/cell/fulltext/S0092-8674(18)31452-1