%0 Journal Article
%T A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex
%J -
%D 2019
%R https://doi.org/10.1016/j.celrep.2019.03.061
%X £¿ LSD2 demethylase binds nucleosomes by discrete promiscuity at multiple sites £¿ Nucleosomal DNA represents an intrinsic barrier to histone demethylation £¿ NPAC has a rigid and catalytically inert oligomerization core and flexible arms £¿ The NPAC/LSD2 multifunctional enzyme complex modifies transcribed chromati
%U https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30391-2