%0 Journal Article
%T Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses
%J -
%D 2019
%R https://doi.org/10.1016/j.isci.2019.01.006
%X £¿ Major glycosylated species exhibit temporal dynamics during fed-batch processes £¿ Key metabolic pathways linked to N-glycosylation exhibit significant temporal dynamics £¿ Dynamics in nucleotide sugar donors (NSDs) directly influences glycoform heterogeneity £¿ Glycoform heterogeneity can be mitigated by supplementing NSD biosynthetic precursor
%U https://www.cell.com/iscience/fulltext/S2589-0042(19)30006-9