%0 Journal Article
%T Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells
%J -
%D 2019
%R https://doi.org/10.1016/j.ccell.2019.01.002
%X £¿ B7-H3 is overexpressed in solid tumors but rarely in normal tissues £¿ B7-H3.CAR T cells show potent antitumor activity against solid tumor cells £¿ 4-1BB co-stimulation in B7-H3.CAR T cells promotes resistance to PD-L1 £¿ B7-H3.CAR T cells are effective in a syngeneic tumor model without causing toxicit
%U https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30002-9