%0 Journal Article
%T A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion
%J -
%D 2019
%R https://doi.org/10.1016/j.ccell.2018.12.013
%X £¿ Sf3b1-K700E mutation impairs 3¡ä splice site selection and induces cellular senescence £¿ Sf3b1-K700E mutation in combination with Atm deletion causes CLL £¿ CLL cells show genome instability and dysregulated BCR signaling £¿ Human CLL cells with SF3B1 mutations show dysregulation of BCR signalin
%U https://www.cell.com/cancer-cell/fulltext/S1535-6108(18)30585-3